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Secondary non-response, which is where Botox becomes less effective as the number of doses are repeated, occurs when Botox injected at high doses (more than 200 U for one treatment) or frequently injected (in a period of less than three months). This is because high doses or frequent doses can create antibodies in the immune system against Botox, making it an ideal conditions for the body to attack Botox proteins. Botox products that contain botulinum toxin combined with other accessory proteins, resistance can be more easily created than pure botulinum toxin products. This is because the area and which are immune cells can attack has increased due to accessory proteins. This concept applies to Korean Botox as well.
People casually use the term “Botox” to describe all of these products, though Botox is a registered trademark that one company owns. How does it work? Botox is a neurotoxin. These substances target the nervous system, disrupting the nerve signaling processes that stimulate muscle contraction. This is how the drug causes temporary muscle paralysis. In order for any muscle to contract, the nerves release a chemical messenger called acetylcholine at the junction where nerve endings meet muscle cells. Acetylcholine attaches to receptors on the muscle cells and causes the cells to contract, or shorten. Botox injections prevent the release of acetylcholine, which stops the muscle cells from contracting. In this way, the toxin helps the muscles to become less stiff.
When Botox is injected around the eyes, it can diffuse into the eyelid muscles and cause droopy eyelids. The affected eyelids will likely return to normal once the effects of the injections wear off, but sleep may suffer in the meantime. If injected around the eyes, Botox can diffuse into the eyelid muscles and cause The affected eyelids will likely return to normal as the effects of the injections wear off but sleep may suffer in the meantime. One of the main causes of insomnia is anxiety. Many Botox fans experience increased anxiety the first few nights after the procedure, which can lead to sleep disturbances.
There are no conclusive studies that suggest a single brand of Botox, Korean or otherwise, has a longer lasting effect than others. The only variation comes in the time needed to see results, with different brands having different “peak” times. But generally speaking, all brands show effect in a similar period of 1 week. The most discussed issue in terms of difference between brands is based on resistance developed by frequent use of Botox by an individual. Dr Siew Tuk Wah, a Singaporean doctor specializing in injectables and non-invasive medical aesthetics, has this issue documented in great detail which you can read in his article, BOTOX vs DYSPORT vs XEOMIN – Differences Between Botulinum Toxin Type A Formulations. See extra info on https://kbeautypharm.com/.